Online reviews can make over-the-counter drugs look way too effective

Here’s one good reason why people often take medications and use health products that don’t live up to expectations or just don’t work — digital word of mouth.

The reviews can be glowing. Take this scuttlebutt about a cholesterol treatment: “I have been using this product for 2 years. Within the first 3 – 4 months my cholesterol was down 30 points. Just got cholesterol tested last week: down from 245 to 196.”

That’s incredible. It might even be true. But the big picture is alarming: Patients’ online reviews of three over-the-counter drugs — two for lowering cholesterol and one for losing weight — greatly exaggerate how well these substances actually work for most people, says psychologist Mícheál de Barra of the University of Aberdeen in Scotland. Online reviewers portray these medications as working three to six times better than they do in clinical trials that randomly assign drugs or placebos to broad samples of volunteers, he says.

“To learn what works in medicine, you need systematically collected data, usually randomized clinical trials,” de Barra says. “It’s very risky to rely on observations and word of mouth, whether it’s electronic or in person.”

Online reviewers probably aren’t lying, at least not in most cases. Neither are online review readers unrealistically optimistic about health treatments. The problem is that people who benefit most from a medication are especially apt to post their experiences online. Review readers get bamboozled by a wave of positive recommendations that don’t accurately represent how a drug works, or doesn’t work, for people in general.

The duping doesn’t end there. Direct word of mouth about medical treatments, as well as glowing testimonials about health products in advertisements, also traffic in positively skewed information.

In some cases, science does, too. Researchers have recently raised alarms about the “file-drawer problem,” in which studies that find no statistical effects are not published (SN: 5/19/12, p. 26). Published studies reporting positive effects then look unjustifiably bulletproof.

Clinical trials can tilt results in other ways as well. Authors of published trials often fail to preregister details of what they plan to study and how they’ll measure it, enabling data manipulation, selective reporting of results and self-serving interpretations of findings. Clinical trials report patients’ “average” responses to, say, an anticholesterol drug, but do a poor job of predicting which individuals will benefit from that treatment. “Published evidence from randomized trials is already an amalgam of evidence-based medicine and hearsay,” notes Stanford University epidemiologist John Ioannidis.
Online reviews are just old-fashioned word of mouth with a global bullhorn. But they offer one way to quantify the positive bias inherent in so much communication about medical treatments. Patients’ medication reviews that include numerical information, such as cholesterol levels before and after taking an anticholesterol drug, represent what Ioannidis calls “evidence-based hearsay.” Even if patients’ reviews rate treatments with a star system rather than including quantified measures of some kind, those opinions become powerful hearsay evidence for other patients, Ioannidis suspects.

De Barra evaluated 908 online reviews of two cholesterol reduction products, Benecol caramel smart chews and CholestOff, written on or before March 18, 2015. He also assessed 767 reviews of a weight-loss drug, Alli (orlistat), written on or before February 28, 2015.

Benecol reviewers reported a not-too-shabby average cholesterol decline of 45 milligrams per deciliter, versus a small average decline of 14 milligrams per deciliter in nine clinical trials. Respective numbers for CholestOff were 31 milligrams per deciliter and 13 milligrams per deciliter. Alli reviewers reported an average weight loss of about 10 kilograms after taking the drug for three months, versus an average of about two or three kilograms in two clinical trials. That disparity widened slightly after taking Alli for seven months.

Each drug garnered mainly positive reviews, some reporting effects far larger than the average, peppered with a few pans, De Barra reports in the March Social Science & Medicine.

What’s particularly concerning is that these three medications displayed small or negligible effects in clinical trials that probably already inflated how well the drugs work, Ioannidis says. So people searching for help in lowering cholesterol or shedding pounds may instead be getting a massive dose of disappointment from online reviews.

Online reviews can also exaggerate a treatment’s worst effects, whether real or alleged. Evidence-based hearsay may be particularly catchy online and in person when it’s frightening, de Barra suspects.

The anti-vaccination movement provides a potent example, due in part to the success of vaccines. When people face no immediate threat from measles or other infectious diseases, anti-vaccine stories may go viral, so to speak, thanks to misapplied but deeply felt intuitions. Two cognitive scientists, Helena Miton of Central European University in Budapest and Hugo Mercier of the Cognitive Sciences Institute in Bron, France, proposed this scenario in the November 2015 Trends in Cognitive Sciences.

However medical treatments acquire halos or horns, only well-conducted, transparent clinical trials can identify effective medical treatments, such as childhood vaccinations, and their potential side effects, Ioannidis says. But an ominous research trend is gathering steam, he warns. Researchers, professional societies, funders and lobbyists increasingly push to replace clinical trials of randomly selected volunteers with studies of interventions for select samples of people who eat certain foods, take certain drugs or behave in certain ways. The latter investigations may inflate a treatment’s effects even more than online patient reviews do, Ioannidis asserts.

Perhaps a new wave of studies showing how evidence-based hearsay misrepresents many medications will be just what the doctor ordered to resuscitate evidence-based medicine, he muses.

Palace remains in Mexico point to ancient rise of centralized power

Remnants of a royal palace in southern Mexico, dating to between around 2,300 and 2,100 years ago, come from what must have been one of the Americas’ earliest large, centralized governments, researchers say.

Excavations completed in 2014 at El Palenque uncovered a palace with separate areas where a ruler conducted affairs of state and lived with his family, say archaeologists Elsa Redmond and Charles Spencer, both of the American Museum of Natural History in New York City. Only a ruler of a bureaucratic state could have directed construction of this all-purpose seat of power, the investigators conclude the week of March 27 in Proceedings of the National Academy of Sciences.

The royal palace, the oldest such structure in the Valley of Oaxaca, covered as many as 2,790 square meters, roughly half the floor area of the White House. A central staircase connected to an inner courtyard that probably served as a place for the ruler and his advisors to reach decisions, hold feasts and — based on human skull fragments found there — perform ritual sacrifices, the scientists suggest. A system of paved surfaces, drains and other features for collecting rainwater runs throughout the palace, a sign that the entire royal structure was built according to a design, the researchers say.

El Palenque’s palace contains no tombs. Its ancient ruler was probably buried off-site, at a ritually significant location, Redmond and Spencer say.

New worm-snail is a super slimer

A new species of worm-snail is rather snotty. Thylacodes vandyensis shoots out strands of mucus that tangle together, building a spiderweb-like trap for plankton and other floating snacks, researchers report April 5 in PeerJ.

Other worm-snails use this hunting technique, but T. vandyensis stands out because of the “copious amounts of mucus” it ejects, says coauthor Rüdiger Bieler. This goo net, which can stretch up to 5 centimeters across, exits the animal’s tentacles at, of course, “a snail’s pace,” jokes Bieler, a curator at the Field Museum of Natural History in Chicago.

Like other worm-snails, T. vandyensis permanently glue themselves to spots. Bieler found T. vandyensis, which typically grow half as tall as a pinkie finger, on the hull of a sunken ship in the Florida Keys. But they don’t belong there: DNA analysis shows that this invasive species’ closest relatives are in the Pacific Ocean. The worm-snail may have made its way to the Atlantic as a stowaway on a ship.

Twisted textile cords may contain clues to Inca messages

Animal-hair cords dating to the late 1700s contain a writing system that might generate insights into how the Inca communicated, a new study suggests.

Researchers have long wondered whether some twisted and knotted cords from the Inca Empire, which ran from 1400 to 1532, represent a kind of writing about events and people. Many scholars suspect that these textile artifacts, known as khipus, mainly recorded decimal numbers in an accounting system. Yet Spanish colonial documents say that some Inca khipus contained messages that runners carried to various destinations.
Now a new twist in this knotty mystery comes from two late 18th century khipus stored in a wooden box at San Juan de Collata, a Peruvian village located high in the Andes Mountains. A total of 95 cord combinations of different colors, animal fibers and ply directions, identified among hundreds of hanging cords on these khipus, signify specific syllables, reports Sabine Hyland. Hyland, a social anthropologist at the University of St. Andrews in Scotland, describes the khipus online April 19 in Current Anthropology.

Her findings support a story told by Collata villagers that the khipus are sacred writings of two local chiefs concerning a late 18th century rebellion against Spanish authorities.

The Collata khipus display intriguing similarities to Inca khipus, including hanging cords with nearly the same proportions of two basic ply directions, Hyland says. A better understanding of Central Andean khipus from the 1700s through the 1900s will permit a reevaluation of the earlier Inca twisted cords, she suggests.

Each Collata khipu, like surviving Inca examples, consists of a horizontal cord from which a series of cords hang. One Collata specimen contains 288 hanging cords separated into nine groups by cloth ribbons tied at intervals along the top cord. The other khipu features 199 hanging cords divided by ribbons into four groups. Knots appear only at cord ends to prevent unraveling. In contrast, proposed accounting khipus contain many knots denoting numbers.

Collata khipus’ initial hanging cords are made of bundles of colored animal hairs that represent the message’s subject matter, Hyland proposes. One khipu starts with a tuft of bright red deer hair, followed by a woven, cone-shaped bundle with metallic-colored thread. The second khipu commences with a woven, tube-shaped bundle of multicolored alpaca hair atop the remains of a red tassel.
“The Collata khipus are completely unlike accounting khipus that I have been studying for over a decade,” Hyland says. Central Andean khipus generally viewed as accounting devices were often made of cotton, and they contain two main colors, between 15 and 39 cord combinations and repetitive knot sequences.

Hyland makes an “excellent case” that these cords represent syllables and probably words as well, says anthropological archaeologist Penelope Dransart of the University of Wales Trinity Saint David in Lampeter.

So far, Hyland has translated the final three cords on one khipu as the word Alluka, the name of a family lineage in Collata. She first talked to villagers and identified the lineage chief that they claimed wrote one of the khipus. Hyland then assigned the three syllables in Alluka to the trio of ending cords, assuming that the sender’s name would appear either there or at the beginning of the message. That enabled her to decipher the final cords on the second khipu as Yakapar, the name of a family lineage in a neighboring village. Heads of these lineages wrote the corded messages, Hyland suspects.

She has not yet deciphered other cords on the two khipus.

Hyland’s insights into 18th century khipus are “profoundly significant,” but won’t help to decipher Inca twisted and knotted cords, predicts Harvard University archaeologist Gary Urton. Collata villagers probably invented a phonetic form of khipu communication after the Inca civilization’s demise, when they were exposed to Spaniards’ alphabetic writing, Urton says. Inca khipus show no signs of cord combinations that corresponded to particular speech sounds, he asserts.

Thanks to the new discoveries, though, “we have hope that at least some khipus might be understood,” says archaeologist Jeffrey Splitstoser of George Washington University in Washington, D.C. Before Hyland’s report, Splitstoser thought it likely that colored threads on khipus had arbitrary meanings assigned by their makers, making them indecipherable. He studies khipus from the Wari empire, which flourished in the Peruvian Andes from around 600 to 1000 (SN: 5/10/03, p. 302).

Officials at several museums with khipu collections have classified as forgeries a few animal-hair specimens that resemble the Collata khipus, Hyland says. Those alleged fakes deserve a closer look for signs of writing, she contends.

Mummy DNA unveils the history of ancient Egyptian hookups

Egyptian mummies are back in style at the summer box office — and in genetics labs. A study of genetic blueprints from 90 mummies repairs the frayed reputation of sarcophagus occupants as sources of ancient DNA. And it reveals evidence of a hookup history with foreigners from the east.

An Egyptian mummy served up the first ancient human DNA sample in 1985 (SN: 4/27/85, p. 262). But both chemicals used in mummification and Egypt’s steamy climate can degrade DNA, and scientists weren’t sure if mummies could supply samples free of modern contamination.

Carefully screening for quality and using the latest in sequencing tech, Verena Schuenemann of the University of Tübingen in Germany and her colleagues extracted and analyzed mitochondrial DNA, which passes from mom to child. They worked primarily with samples from teeth and bones, rather than from soft tissue. Three mummies yielded readable samples of DNA from cell nuclei, which includes DNA from both parents. The mummies ranged in age of origin from 1388 B.C. to A.D. 426.

The analysis reveals genetic ties to the Middle East and Greece — not a huge surprise since Egypt was a center of travel and trade at that time. The conspicuous absence of genetic connections to sub-Saharan Africa seen in modern Egyptians points to a later influx of foreigners from that region, the researchers write May 30 in Nature Communications.

Launch your imagination with Science News stories

Imagine for a moment that you lived on another planet. Not Tatooine, Trantor or another fictional orb, but a real-deal planet circling a star somewhere in our real-deal galaxy. What would your world look like? Would there be a rocky surface? An atmosphere? How long would a day last? How about a year? What special physiology might you need to survive there? There’s no single scenario, of course. Starting with some basic facts, you can speculate in all sorts of surprising directions. That’s the fun of the exercise.

Over the last quarter century or so, astronomers have confirmed more than 3,600 exoplanets — that’s 3,600-plus worlds in addition to the planets, moons and other heavenly bodies known in our own solar system. People have long imagined what it would be like to live on Mars, and bold thinkers have dared to envision an existence on, say, Jupiter (see “Juno spacecraft reveals a more complex Jupiter“). Today there are many more possibilities, including planets orbiting dim red stars very different from our sun. In “Life might have a shot on planets orbiting dim red stars,” Christopher Crockett describes the hurdles life might face in evolving and surviving near these cool stars. On planets orbiting Proxima Centauri, TRAPPIST-1 and other M dwarfs, water could be extremely sparse, energetic flares might regularly singe the surface and you might live always in sun or forever in darkness.
Reading about these worlds, I’d say, is better than fiction — as is a lot of what Science News covers. You don’t need a novel or a movie to escape into what feels like another reality. Just flip through these pages. The stories will take you to other worlds, as well as inner, hidden ones. Former Science News intern Elizabeth S. Eaton writes about the bacteria that infect our bodies and the problem of antibiotic resistance. Picturing these invisible, single-celled organisms wreaking havoc in the body, unchecked by our best medicines, gives me goose bumps. Eaton’s story is about the battle that would ensue if predatory bacteria are sent in to hunt down and kill these bad guys, as some researchers have proposed. One researcher likens the bacteria to the antagonists in the Alien films. There’s true cinematic potential.

And it doesn’t end there. Bruce Bower takes readers into the past, to the roots of the human evolutionary tree. Most scientists think Africa was the birthplace of hominids, but new research suggests it could have been Europe. And Susan Milius offers an opportunity to consider what it might be like to live in another type of body — a flamingo’s. The birds have an off-kilter shape, with ankles where we’d expect knees. For flamingos, Milius reports, standing on one leg might be more stable than standing on two. After reading the story, I couldn’t help but attempt to balance on just my right foot, in hopes of getting a handle on human-flamingo differences. (It was an unsuccessful 20 seconds. Thank goodness my office door was closed.)

Every issue of Science News includes similar inspiration. There’s serious stuff to be sure, but there are plenty of chances to ponder the strangeness of reality — and to stretch it. After thinking about living on Proxima b or being a wading bird, consider being a wading bird on Proxima b. For fuel to help your imagination run, you’ve come to the right place.

This glass frog wears its heart for all to see

A newly discovered glass frog from Ecuador’s Amazon lowlands is giving researchers a window into its heart.

Hyalinobatrachium yaku has a belly so transparent that the heart, kidneys and urine bladder are clearly visible, an international team of researchers reports May 12 in ZooKeys. Researchers identified H. yaku as a new species using field observations, recordings of its distinct call and DNA analyses of museum and university specimens.

Yaku means “water” in Kichwa, a language spoken in Ecuador and parts of Peru where H. yaku may also live. Glass frogs, like most amphibians, depend on streams. Egg clutches dangle on the underside of leaves, then hatch, and the tadpoles drop into the water below. But the frogs are threatened by pollution and habitat destruction, the researchers write. Oil extraction, which occurs in about 70 percent of Ecuador’s Amazon rainforest, and expanding mining activities are both concerns.

Fire ants build towers with three simple rules

When faced with rushing floodwaters, fire ants are known to build two types of structures. A quickly formed raft lets the insects float to safety. And once they find a branch or tree to hold on to, the ants might form a tower up to 30 ants high, with eggs, brood and queen tucked safely inside. Neither structure requires a set of plans or a foreman ant leading the construction, though. Instead, both structures form by three simple rules:

If you have an ant or ants on top of you, don’t move.
If you’re standing on top of ants, keep moving a short distance in any direction.
If you find a space next to ants that aren’t moving, occupy that space and link up.
“When in water, these rules dictate [fire ants] to build rafts, and the same rules dictate them to build towers when they are around a stem [or] branch,” notes Sulisay Phonekeo of the Georgia Institute of Technology in Atlanta. He led the new study, published July 12 in Royal Society Open Science.

To study the fire ants’ construction capabilities, Phonekeo and his Georgia Tech colleagues collected ants from roadsides near Atlanta. While covered in protective gear, the researchers dug up ant mounds and placed them in buckets lined with talc powder so the insects couldn’t climb out. Being quick was a necessity because “once you start digging, they’ll … go on attack mode,” Phonekeo says. The researchers then slowly flooded the bucket until the ants floated out of the dirt and formed a raft that could be easily scooped out.

In the lab, the researchers placed ants in a dish with a central support, then filmed the insects as they formed a tower. The support had to be covered with Teflon, which the ants could grab onto but not climb without help. Over about 25 minutes, the ants would form a tower stretching up to 30 mm high. (The ants themselves are only 2 to 6 mm long.)
The towers looked like the Eiffel Tower or the end of a trombone, with a wide base and narrow top. And the towers weren’t static, like rafts of ants are. Instead, videos of the ant towers showed that the towers were constantly sinking and being rebuilt.

Peering into the transparent Petri dish from below revealed that the ants build tunnels in the base of a tower, which they use to exit the base before climbing back up the outside.

“The ants clear a path through the ants underneath much like clearing soil,” Phonekeo says. Ants may be using the tunnels to remove debris from inside the towers. And the constant sinking and rebuilding may give the ants a chance to rest without the weight of any compatriots on their backs, he says.

To find out what was happening inside the tower, the researchers fed half their ants a liquid laced with radioactive iodide and then filmed the insects using a camera that captured X-rays. In the film, radioactive ants appeared as dark dots, and the researchers could see that some of those dots didn’t move, but others did.

The team then turned to the three rules that fire ants follow when building a raft and realized that they also applied to towers. But there was also a fourth rule: A tower’s stability depends on the ants that have attached themselves to the rod. The top row of ants on the rod aren’t stable unless they form a complete ring. So to get a taller tower, there needs to be a full ring of ants gripping to the rod and each other.

That such simple rules could form two completely different structures is inspiring to Phonekeo. “It makes me wonder about the possibilities of living structures that these ants can build if we can design the right environment for them.”

What Curiosity has yet to tell us about Mars

After five years on Mars, the Curiosity rover is an old pro at doing science on the Red Planet. Since sticking its landing on August 5, 2012, NASA’s Little Robot That Could has learned a lot about its environs.

Its charge was simple: Look for signs that Gale crater, a huge impact basin with a mountain at its center, might once have been habitable (for microbes, not Matt Damon). Turning over rocks across the crater, the rover has compiled evidence of ancient water — a lake fed by rivers once occupied the crater itself — and organic compounds and other chemicals essential for life.
NASA has extended the mission through October 2018. And there’s still plenty of interesting chemistry and geology to be done. As the robot continues to climb Mount Sharp at the center of the crater, Curiosity will explore three new rock layers: one dominated by the iron mineral hematite, one dominated by clay and one with lots of sulfate salts.

So, here are four Martian mysteries that Curiosity could solve (or at least dig up some dirt on).

Does Mars harbor remnants of ancient life?
Curiosity’s Mars Hand Lens Imager can take microscopic images, but preserved cells or microfossils would still have to be pretty big for the camera to see them. What the rover can do is detect the building blocks for those cells with its portable chemistry lab, Sample Analysis at Mars. The lab has already picked up chlorobenzene, a small organic molecule with a carbon ring, in ancient mud rock. Chains of such molecules go into making things like cell walls and other structures.
“We’ve only found simple organic molecules so far,” says Ashwin Vasavada, a planetary scientist at NASA’s Jet Propulsion Laboratory who leads Curiosity’s science team. Detective work in chemistry labs here on Earth could shed light on whether bigger organic molecules on Mars’ surface might degrade into smaller ones like chlorobenzene.

Curiosity could still turn up intact, heavier-duty carbon chains. The rover carries two sets of cups to do chemistry experiments, one dry and one wet. The latter contains chemical agents designed to draw out hard-to-find organic compounds. None of the wet chemistry cups have yet been used. A problem with Curiosity’s drill in December 2016 has held up the search for organics, but possible solutions are in the works.
How did Mars go from warm and wet to cold and dry?
That’s one of the million-dollar questions about the Red Planet. Curiosity has piled on evidence that Mars was once a much more hospitable place. Around 3.5 billion years ago, things changed.

The going theory is that particles from the sun stripped away much of Mars’ atmosphere (and continues to do so) when the planet lost most of its protective magnetic field. “That caused the climate to change from one that could support water at the surface to the dry planet it is today,” Vasavada explains. Curiosity found a higher ratio of heavy elements in the current atmosphere, adding credence to this argument — presumably the lighter elements were the first to go.

There’s also a chance that as the rover hikes up Mount Sharp it could capture regional evidence of the wet-to-dry transition. So far, Curiosity has investigated rocks from the tail end of the wet period. The new geologic layers it will encounter are younger.

“Hopefully we’ll be able to get some insight by looking at these rocks into some of the global changes happening that maybe no longer permitted a lake to be present on the surface,” says Abigail Fraeman, a research scientist at NASA’s Jet Propulsion Lab.
Does Mars really have flowing water today?
Some mineralized salts absorb water and release it as liquid when they break down at certain temperatures. The Curiosity team looked for the bursts of water that might result from such a process in Gale crater and came up empty.

But in 2015, the Mars Reconnaissance Orbiter snapped images of shifting salt streaks indicative of actively flowing water. The images are the best evidence yet that liquid water might not be a thing of the past.

Mount Sharp has similar dark streaks, and Curiosity periodically takes pictures of them. “It’s something we keep an eye on,” Vasavada says. If the streaks change in a way that might indicate that they’re moving, the rover could corroborate evidence of modern-day water on Mars. But so far, the streaks have stayed stagnant.

Where does the methane in Mars’ atmosphere come from?
On Earth, microbes are big methane producers, but on Mars, methane’s origins are still unclear. Early on Curiosity detected extremely low levels of the gas in Mars’ atmosphere. This baseline appears to subtly fluctuate annually — perhaps driven by temperature or pressure. Curiosity continues to monitor methane levels, and more data and modeling could help pinpoint what’s behind the annual ups and downs.

At the end of 2014, researchers noticed a spike 10 times the baseline level. Scientists suspect that methane sticks around in the air on Mars for only about 300 years. So, the methane spike must be relatively new to the atmosphere. “That doesn’t necessarily mean it’s being actively created,” Vasavada says. “It could be old methane being released from underground.” Minerals interacting with subterranean water sometimes make methane gas.

Mars’ methane could also be the product of planetary dust particles broken down on the surface. And yet another possible explanation is biological activity. “We have zero information to know whether that’s happening on Mars, but we shouldn’t exclude it as an idea,” says Vasavada. So, Martian life is unlikely but can’t be completely ruled out.

These spiders crossed an ocean to get to Australia

If you look at a map of the world, it’s easy to think that the vast oceans would be effective barriers to the movement of land animals. And while an elephant can’t swim across the Pacific, it turns out that plenty of plants and animals — and even people — have unintentionally floated across oceans from one continent to another. Now comes evidence that tiny, sedentary trapdoor spiders made such a journey millions of years ago, taking them from Africa all the way across the Indian Ocean to Australia.

Moggridgea rainbowi spiders from Kangaroo Island, off the south coast of Australia, are known as trapdoor spiders because they build a silk-lined burrow in the ground with a secure-fitting lid, notes Sophie Harrison of the University of Adelaide in Australia. The burrow and trapdoor provides the spiders with shelter and protection as well as a means for capturing prey. And it means that the spiders don’t really need to travel farther than a few meters over the course of a lifetime.

There was evidence, though, that the ancestors of these Australian spiders might have traveled millions of meters to get to Australia — from Africa. That isn’t as odd as it might seem, since Australia used to be connected to other continents long ago in the supercontinent Gondwana. And humans have been known to transport species all over the planet. But there’s a third option, too: The spiders might have floated their way across an ocean.

To figure out which story is most likely true, Harrison and her colleagues looked at the spider’s genes. They turned to six genes that have been well-studied by spider biologists seeking to understand relationships between species. The researchers looked at those genes in seven M. rainbowi specimens from Kangaroo Island, five species of Moggridgea spiders from South Africa and seven species of southwestern Australia spiders from the closely related genus Bertmainius.

Using that data, the researchers built a spider family tree that showed which species were most closely related and how long ago their most recent common ancestor lived. M. rainbowi was most closely related to the African Moggridgea spiders, the analysis revealed. And the species split off some 2 million to 16 million years ago, Harrison and her colleagues report August 2 in PLOS ONE.

The timing of the divergence was long after Gondwana split up. And it was long before either the ancestors of Australia’s aboriginal people or later Europeans showed up on the Australian continent. While it may be improbable that a colony of spiders survived a journey of 10,000 kilometers across the Indian Ocean, that is the most likely explanation for how the trapdoor spiders got to Kangaroo Island, the researchers conclude.

Such an ocean journey would not be unprecedented for spiders in this genus, Harrison and her colleagues note. There are three species of Moggridgea spiders that are known to live on islands off the shore of the African continent. Two live on islands that were once part of the mainland, and they may have diverged at the same time that their islands separated from Africa. But the third, M. nesiota, lives on the Comoros, which are volcanic islands. The spiders must have traveled across 340 kilometers of ocean to get there.
These types of spiders may be well-suited to ocean travel. If a large swatch of land washes into the sea, laden with arachnids, the spiders may be able to hide out in their nests for the journey. Plus, they don’t need a lot of food, can resist drowning and even “hold their breath” and survive on stored oxygen during periods of temporary flooding, the researchers note.